Table 2.

Assessment of phenotypical and functional attributes of ex vivo-expanded bone marrow-derived MSCs

Patient ID	Expansion cyclesa	Fulfillment of “minimal phenotypical” markersb	Functional markersc
			CPD	FFS
#1	2	Yes	1.2/1.2	92/94
#2	3	Yes	1.5/1.5	93/95
#3	2	Yes	1.8/1.7	92/95
#4	3	Yes	1.6/1.5	93/95
#5	2	Yes	1.4/1.4	92/94

Notes:

^aRequired to manufacture the cell product.

^bDominici et al.18

^cAs assessed20 at the end of the first and last ex vivo expansion cycle.

Abbreviations: CPD, cumulative population doubling; FFS, fast forward scatter.