Table 7.
Analysis time point related PRO measure | Core ASD symptoms | Social communication | Restrictive repetitive behaviors | Mental health | Self-regulation | Challenging behavior |
---|---|---|---|---|---|---|
ABI SCALE | ||||||
Baseline (N = 139) | ||||||
SRS-2 (Caregiver) | ||||||
Total score | 0.81 | 0.65 | 0.74 | 0.50 | 0.47 | 0.35 |
Social communication and interaction | 0.80 | 0.68 | 0.69 | 0.48 | 0.43 | 0.32 |
Restricted interests/repetitive behavior | 0.71 | 0.46 | 0.76 | 0.49 | 0.52 | 0.41 |
CASI-Anx | ||||||
Anxiety scale score | 0.54 | 0.34 | 0.58 | 0.78 | 0.38 | 0.25 |
RBS-R | ||||||
Overall score | 0.68 | 0.40 | 0.77 | 0.45 | 0.52 | 0.42 |
ABC-Community | ||||||
Irritability/agitation | 0.50 | 0.26 | 0.61 | 0.56 | 0.68 | 0.81 |
Lethargy/social withdrawal | 0.70 | 0.69 | 0.52 | 0.35 | 0.17 | 0.19 |
Stereotypic behavior | 0.60 | 0.40 | 0.64 | 0.36 | 0.53 | 0.42 |
Hyperactivity/non-compliance | 0.44 | 0.23 | 0.54 | 0.30 | 0.88 | 0.54 |
Inappropriate speech | 0.59 | 0.33 | 0.69 | 0.40 | 0.65 | 0.48 |
ABC, Aberrant Behavior Checklist; ABI, autism behavior inventory; ASD, autism spectrum disorder; CASI-Anx, Child Adolescent Symptom Inventory – Anxiety; PRO, Patient Reported Outcome; RBS-R, Repetitive Behavior Scale – Revised; SRS-2, Social Responsiveness Scale 2; ZBI, Zarit Burden Interview.