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. 2019 Feb 27;13:77. doi: 10.3389/fnins.2019.00077

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Copyright © 2019 Alvarado, Fuentes-Santamaría, Gabaldón-Ull and Juiz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examples of ABR waveforms from NE (A–D) and E (E–H) rats at all ages and frequencies evaluated. The NE3 (A), NE6 (B), and E3 © animals, previous any noise exposure, showed typical waveform patterns which consisted of 4 to 5 evoked waves after stimulus onset. At 12 (C) and 18 (D) months of age, NE rats had an age-related decrease in wave amplitudes at all frequencies. However, in the exposed animals such a reduction was already apparent at 6 months (F) and it was more evident at 12 (G) and 18 (H) months of age for the higher frequencies when compared to NE rats.