Table 1:
Demographics and cognitive test performance (mean [S.D.]) at clinic visit corresponding to year of Tau and Aβ PET imaging for the entire sample and classified by dichotomous Aβ status. Mean and standard deviation are listed for continuous variables.
| All Participants | Aβ- | Aβ+ | |
|---|---|---|---|
| N | 137 | 97 | 40 |
| Age at Tau PET scan# | 76.32 (6.22) Range=65–90 |
75.54 (6.41) Range=65–90 |
78.20 (5.34) Range=68–88 |
| Female Sex | 79 | 55 | 24 |
| Years of Education | 15.85 (2.95) | 15.75 (3.07) | 16.10 (2.67) |
| APOE ɛ4 non-carrier/APOE ɛ4 carrier* | 94/43 | 81/16 | 13/27 |
| Total Prospective Follow Up Time (years)# | 2.05 (0.74) | 2.09 (0.72) | 1.94 (0.76) |
| Total number of cognitive test visits | 2.8 (1.1) | 2.8 (1.2) | 2.8 (1.1) |
| MMSE | 29.18 (1.04) | 29.29 (0.98) | 28.92 (1.14) |
| Logical Memory Delayed Recall WMS IIa** | 15.75 (3.92) | 16.30 (3.81) | 14.43 (3.93) |
Age difference p<0.05 between Aβ- and Aβ + groups.
Total prospective follow up time was defined using the neuropsychological testing session within one year of the Tau PET as the “baseline” visit and comparing that date to the date of the final subsequent neuropsychological testing session. Likewise, the tabulated MMSE and Logical Memory values reflect scores from the neuropsychological testing session within one year of the date of the tau scan.
Logical Memory performance difference p<0.05 between Aβ- and Aβ + groups.