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. 2019 Mar 6;14(3):e0212228. doi: 10.1371/journal.pone.0212228

Table 4. Detection of recurrent translocations in DNA samples by different NGS algorithms.

ID Chromosome RT-PCR NGS, BreakDancer NGS, Delly
P9 46,XY[20] SET-NUP214 Detected Detected
P11 45,X,-Y,t(8;21)(q22;q22)[20]/46,XY[4] RUNX1-RUNX1T1 - Detected
P12 46,XY,t(15;17)(q24;q21)[7] PML-RARA - Detected
P13 46,XX,t(15;17)(q24;q21)[19]/46,XX[1] PML-RARA - -
P14 47,XX,+8,t(15;17)(q24;q21)[20] PML-RARA - Detected
P15 46,XY,t(11;17)(q23;q21)[3]/47,sl,+8[7]/46,XY[10] ZBTB16-RARA - -
p18 46,XX[20] KMT2A-MLLT3 - -
P19 Not tested CBFB-MYH11 - -
P20 46,XX,+del(1)(p13),-16,der(21)t(16;21)(p11;q22) FUS-ERG - Detected
P23 45,X,-Y,t(8;21)(q22;q22)[20] RUNX1-RUNX1T1 - Detected
P26 47,XX,+8,inv(16)(p13q22)[22] CBFB-MYH11 Detected Detected
P27 No mitotic cells RUNX1-RUNX1T1 - Detected
P34 46,XY[20] RUNX1-RUNX1T1 - Detected
P36 46,XX,inv(16)(p13q22)[19]/46,XX[9] CBFB-MYH11 Detected Detected
P43 46,XY,del(9)(q22)[6]/46,XY[17] RUNX1-RUNX1T1 - Detected
P45 46,XX,t(15;17)(q24;q21)[22]/46,XX[2] PML-RARA - Detected
P47 45,X,-Y,t(8;21)(q22;q22)[21] RUNX1-RUNX1T1 - Detected
P72 46,XX,t(8;21)(q22;q22)[20] RUNX1-RUNX1T1 - -
P73 46,XX,t(8;21)(q22;q22)[20] RUNX1-RUNX1T1 - Detected
P82 46,XY,t(15;17)(q24;q21)[5]/46,idem,del(7)(q22)[7]/46,XY[1] PML-RARA - Detected
P83 46,XY,t(15;17)(q24;q21)[16]/46,XY[4] PML-RARA - Detected
P84 46,XY,t(15;17)(q24;q21)[16]/46,XY[4] PML-RARA - Detected
P117 46,XX[20] PML-RARA - -
P123 46,XY,t(8;21)(q23;q22)[11]/46,XY[9] RUNX1-ZFPM2 - -
P131 46,XX,t(15;17)(q24;q21)[20] PML-RARA - -
P134 47,XX,+8,t(10;11)(p13;q21)[20] KMT2A-MLLT10 - -