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. 2019 Feb 15;10(14):1458–1472. doi: 10.18632/oncotarget.26680

Figure 5. Tumor protection in post-challenge vaccinated mice.

Figure 5

Mice were challenged with CT26 cells and subsequently received vaccinations with Ad5-MelARV. PBS injected mice served as negative controls (light grey lines) (n = 8). Each line represents a single mouse in the course of the experiment. (A) Mice were vaccinated on day 2 post challenge (d.2 p.c.) with a single dose of Ad5-MelARV (n = 7). (B) Additionally to the vaccination on d.2 p.c., mice received an anti-PD-1 treatment starting on day 8 after the challenge and repeated anti-PD-1 injections on days 12, 16 and 20 (n = 7). (C) As a negative control, mice received only anti-PD-1 treatment (n = 7).