Table 2.
Characteristics of DHF hospitalization (n = 25)*
| Dengue grade (adjusted WHO 1997; n, %) | |
| Dengue fever | 0 (0) |
| Dengue hemorrhagic fever grade I | 6 (24) |
| Dengue hemorrhagic fever grade II | 5 (20) |
| Dengue hemorrhagic fever grade III (DSS) | 7 (28) |
| Dengue hemorrhagic fever grade IV (DSS) | 7 (28) |
| Dengue grade (WHO 2009; n, %) | |
| Dengue fever without warning signs | 1 (4) |
| Dengue fever with warning signs | 10 (40) |
| Severe dengue | 14 (56) |
| Age at hospitalization (years) | 6.9 (2.8–8.8) |
| Time between hospitalization and current measurements (years) | 8.4 (0.8–16.5) |
| Duration of hospitalization (days) | 4.4 (3–8) |
| Presence of plasma leakage (n, %) | 22 (88) |
| Presence of mucosal bleeding manifestations (n, %) | 4 (16) |
| Presence of gastrointestinal bleeding manifestations (n, %) | 3 (12) |
| Presence of dermal bleeding manifestations (n, %) | 12 (48) |
| Presence of pleural effusion (n, %) | 4 (16) |
| Presence of encephalopathy (n, %) | 1 (4) |
| Presence of other severe complications (n, %)† | 3 (12) |
| Presence of dengue IgM antibodies (%) | 56 |
| Presence of dengue IgG antibodies (%) | 80 |
| Mean lowest recorded hematocrit (%)‡ | 32.6 (16.6–45.3) |
| Mean highest recorded hematocrit (%)‡ | 43.6 (30.0–56.0) |
| Mean ∆-hematocrit (%)‡,§ | 39.7 (4.9–123.8) |
| Mean lowest recorded thrombocyte count (cells/µL)‡ | 42,929 (6,000–89,000) |
| Mean highest recorded thrombocyte count (cells/µL)‡ | 98,088 (44,100–206,000) |
| Mean ∆-thrombocyte count (%)‡,§ | 225.8 (14.6–1,250.0) |
| Mean highest recorded leukocyte count (cells/mm3) | 13,468 (3,300–127,000) |
| Mean lowest systolic blood pressure (mmHg) | 97.9 (70–120) |
| Mean lowest diastolic blood pressure (mmHg) | 58.0 (32–80) |
| Mean lowest mean arterial pressure (mmHg) | 71.3 (50–93) |
| Crystalloid fluid management (%) | |
| Maintenance (Ringer’s lactate) | 6 (24) |
| Maintenance (dextrose + NaCl) | 2 (8) |
| 10% rehydration deficit (Ringer’s lactate) | 17 (68) |
| Presence of colloid transfusion (%) | 5 (20) |
DHF = dengue hemorrhagic fever; DSS = dengue shock syndrome. All values are mean (range), unless otherwise indicated.
* Clinical data on the hospitalization period were not available for three participants and these are, therefore, not included in this table.
† Three of 25 participants had renal impairment as a complication of DHF.
‡ One participant had only one reported value of hematocrit and thrombocyte count and is not included in the mean data of those parameters, but is included in the other parameters.
§ Expressed as “(highest value–lowest value)/lowest value * 100%.”