Figure 3.
Phylogenetic trees comparing complete S (A), M (B), and L (C) segment sequences of RVFV using all available full genome sequences. The sequence from the three RT-PCR–positive acute human cases described here, 20160187 (AC1), 201601298 (AC2), and 201601502 (AC4), are in red type. The evolutionary history was inferred based on the SPR model with the GTR + Γ (n = 4) nucleotide substitution model. The tree is drawn to scale, with branch lengths measured in the number of substitutions per site. Branch support estimates represent bootstrap values following 1,000 replicates and are displayed as integers for branch support > 70%. Clades are labeled according to Bird et al.24, 26 and Aradaib et al.27 Evolutionary analyses were conducted using phyml (v 3.0). Scale bar represents 0.005 substitutions/site. GenBank accession numbers used in tree are MG953418, MG953419, MG953420, MG953421, MG953422, MG953423, MG953424, MG953425, and MG953426. RT-PCR = reverse transcriptase polymerase chain reaction; RVFV = Rift Valley fever virus. This figure appears in color at www.ajtmh.org.