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. Author manuscript; available in PMC: 2020 Mar 5.
Published in final edited form as: Cell Metab. 2019 Jan 24;29(3):736–744.e7. doi: 10.1016/j.cmet.2018.12.022

Scheme 1.

Scheme 1.

Synthesis of dendrons. Reagents and conditions: (a) CDMT, N-methylmorpholine, DMF, r.t., 48 h (82%); (b) TFA/THF~2:1, r.t., 12 h (85%); (c) HBTU, DIPEA, DMF, r.t., 48 h (75%).