Table 3.

Change from Baseline for Self-Report Outcomes

Self-Report Measure	Time Point (wks)	LS Mean Change [95% CI]				Trt Diffb
		Oxytocin N = 32		Placebo N = 30
Interpersonal Reactivity Index
Fantasy	6	−0.8	[−2.4, 0.8]	−1.5	[−3.1, 0.1]	0.7
	12	−1.3	[−2.9, 0.4]	−1.1	[−2.7, 0.5]	−0.2
Emotional Concern	6	−1.2	[−2.5, 0.1]	−1.4a	[−2.7, −0.1]	0.2
	12	−1.2	[−2.5, 0.1]	−1.1	[−2.3, 0.2]	−0.1
Perspective Taking	6	−0.4	[−1.9, 1.0]	−1.4	[−2.8, 0.1]	1
	12	0.4	[−1.1, 1.9]	−1.8a	[−3.3, −0.4]	2.2
Personal Distress	6	0.6	[−0.9, 2.1]	−0.4	[−1.8, 1.1]	1
	12	0.2	[−1.3, 1.7]	−0.3	[−1.8, 1.1]	0.5
Lieberman Anxiety Scale
Total	6	−0.3	[−8.3, 7.7]	−1.6	[−9.7, 6.4]	1.3
	12	−1.3	[−9.6, 6.9]	−8.0	[−16.1, 0.2]	6.7
Fear	6	−0.2	[−4.6, 4.2]	1.7	[−2.7, 6.0]	−1.9
	12	−0.7	[−5.2, 3.8]	−1.6	[−5.9, 2.8]	0.9
Avoidance	6	−0.1	[−4.3, 4.0]	−3.7	[−7.8, 0.5]	3.6
	12	−0.6	[−4.9, 3.7]	−5.4	[−9.5, −1.3]	4.8
Social Fear	6	−0.1	[−2.4, 2.2]	−0.1	[−2.4, 2.2]	0
	12	−0.6	[−2.9, 1.8]	−1.4	[−3.7, 0.9]	0.8
Social Avoidance	6	0.4	[−1.6, 2.3]	−1.2	[−3.1, 0.8]	1.6
	12	−0.1	[−2.0, 1.9]	−2.7a	[−4.6, −0.7]	2.6
Performance Fear	6	−0.1	[−2.6, 2.3]	1.7	[−0.7, 4.2]	−1.8
	12	−0.2	[−2.7, 2.4]	−0.2	[−2.6, 2.2]	0
Performance Av	6	−0.5	[−2.9, 1.8]	−1.1	[−3.4, 1.3]	0.6
	12	−0.6	[−3.0, 1.8]	−1.9	[−4.2, 0.5]	1.3
Green Paranoid Thought Scale
Social Reference	6	−0.3	[−3.8, 3.2]	−4.7a	[−8.2, −1.2]	4.4
	12	−0.3	[−3.8, 3.3]	−3.5	[−6.9, 0.1]	3.2
Persecution	6	−0.2	[−4.1, 3.9]	−3.4	[−7.4, 0.6]	3.2
	12	−0.9	[−5.0, 3.3]	−2.1	[−6.1, 1.8]	1.2
Total	6	−0.4	[−6.9, 6.2]	−8.1a	[−14.6, −1.7]	7.7
	12	−1.0	[−7.7, 5.7]	−5.6	[−12.1, 0.8]	4.6

Note: Bold values indicate significant between group differences, p <.05.

^aIndicates significant within group differences.

^bValues reflect differences between treatment groups, i.e., oxytocin group compared with the placebo group, at each time point. Models adjusted for baseline value, age, and baseline PANSS social items.