Table 1.

Least Squares Means Estimates of Brief Psychiatric Rating Scale (BPRS) Total Scores Over Time

	Placebo		Omega 3		Treatment-by-time interaction				Effect of Treatment
	Mean	SE	Mean	SE	F	df	df	P	F	df	df	p
Entire sample (N=50)1
Baseline	42.3200	1.5717	41.8000	1.4485	0.65	10	312	0.7728	3.03	1	312	0.0826
week 16	28.8419	2.0808	24.0912	1.8734
Restricted to participants who did not receive lorazepam (N=23)2
Baseline	42.0833	2.2528	43.6364	2.0395	1.71	10	117	0.0867	4.29	1	117	0.0406
week 16	33.5130	3.6285	23.8372	2.5976
Restricted to participants who received lorazepam at any point (N=27)3
Baseline	42.5385	2.1782	40.3571	2.0063	0.33	10	175	0.9721	0.81	1	175	0.3691
week 16	26.5460	2.5505	23.7965	2.6232

¹effect of time, F=24.36, df=10, 312; p<0.0001

²effect of time, F=9.85, df=10, 117; p<0.0001

³effect of time, F=17.14, df=10, 175; p<0.0001