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. 2019 Mar;5(1):118–126. doi: 10.18383/j.tom.2018.00035

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© 2019 The Authors. Published by Grapho Publications, LLC

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure 4. — Representative images from radiation plans from 2 different patients. The top row depicts images of radiation plans using advanced MRI to boost tumor subregions to 75 Gy. High-risk tumor targets are identified by advanced MRI (cyan) beyond the abnormal regions seen on T1 Gd-enhanced conventional MRI (green). The conformal 75-Gy isodose line targeting the advanced imaging tumor volume is depicted in red, and the larger 60-Gy isodose line targeting the anatomic T1-Gd-enhanced region with standard clinical margins is depicted in gray-white. The bottom row depicts images of comparison standard radiation plans for the same patients based on anatomic T1-Gd-enhanced MRI with standard clinical margins prescribed to 60 Gy. As showed, advanced MRI-identified boost regions prescribed to 75 Gy were often contained within standard anatomic MRI regions prescribed to 60 Gy.