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A co-occurrence network analysis among the microbiota and metabolites. Each co-occurring pair among microbial populations at the genus level and metabolites has an absolute Spearman rank correlation above 0.72 [red dotted line, positive correlation (r ≥ 0.72); blue dotted line, negative correlation (r ≤ –0.72)] with a false discovery rate-corrected significance level under 0.05. Microbes are shown by red V-shaped nodes, and metabolites are shown by green round nodes.
