Table 2.
Baseline characteristics of patients and healthy volunteers in the flow cytometry and longitudinal components of the study.
| Flow Cytometry | Longitudinal | |||
|---|---|---|---|---|
| HV (n = 12) | IBS (n = 12) | HV (n = 15) | IBS-D (n = 7) | |
| Age (years) | 50.6 ± 2.3 | 46.3 ± 4.1 | 49.2 ± 1.9 | 40.7 ± 5.1 |
| Female Sex | 83.3% | 75.0% | 93.3% | 57.1% |
| BMI | 25.1 ± 0.9 | 33.2 ± 1.8** | 24.4 ± 0.7 | 29.8 ± 3.9 |
| IBS-SSS | 12.5 (0–29.3) | 237.0 (195.5–342.0)*** | 13.0 (0–30.0) | 306.0 (229.0–389.0)$ |
| IBS-QOL | 0.4 (0–4.5) | 113.5 (69.8–130.8)*** | 0 (0–1.6) | 112.0 (81.0–150.0)# |
HV: Healthy Volunteers. IBS: Irritable bowel syndrome. IBS-D: diarrhoea-predominant IBS, IBS-SSS: IBS Symptom Severity Score. IBS-QOL: IBS-36 Quality of Life. BMI: Body mass index. Age and BMI data expressed as Mean ± SEM **p = 0.0030 vs. HV, $p = 0.0002 vs. HV, #p = 0.0001 vs. HV and ***p < 0.0001 vs. HV.