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. 2019 Mar 6;9:3743. doi: 10.1038/s41598-019-40283-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the patients’ EDSS score with regard to polypharmacy and patient care. Comparing Pw/oP (N = 133) and PwP (N = 173) (according to all medications) as well as outpatients (N = 146) and inpatients (N = 160), the boxplot shows the distribution of the patients’ degree of disability for each subgroup. The upper and lower quartiles of the EDSS ratings are marked by the boxes. The whiskers range to the minimum and maximum values, while the medians are indicated by horizontal lines. EDSS, expanded disability status scale; N, number of patients; p, p-value; PwP, patients with polypharmacy; Pw/oP, patients without polypharmacy; ^UMann-Whitney U test.