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. 2019 Mar 6;9:3651. doi: 10.1038/s41598-019-40247-9

Table 1.

Standard measures of the Poincaré plots of RR and QT intervals represented by min-max, median, and interquartile range (Q1–Q3). The values are obtained over n = 18 ECG samples, and those of IBIs and FPDs of the hiPSC-CM aggregates, obtained over n = 21 IBI and n = 20 FPD time series. p-values are computed using independent two-sample t-test.

Measures ECG, RR (n = 18) hiPSC-CMs, IBI (n = 21) p-value
min-max, median, (Q1–Q3) min-max, median, (Q1–Q3)
Mean (ms) 871–1830 703–2383 0.0207
1092 1400
(1044–1232) (1178–1745)
SD1/SD2 (n.u) 0.15–0.54 0.03–0.98 0.749
0.28 0.28
(0.22–0.33) (0.16–0.45)
Pearson’s r (n.u) 0.55–0.96 −0.02–1.00 0.483
0.85 0.85
(0.80–0.91) (0.67–0.95)
Measures ECG, QT ( n  = 18) hiPSC-CMs, FPD ( n  = 20) p-value
min-max, median, (Q1–Q3) min-max, median, (Q1–Q3)
Mean (ms) 377–501 394–1529 <0.001
419 902
(406–434) (764–982)
SD1/SD2 (n.u) 0.21–0.83 0.13–0.98 0.023
0.45 0.72
(0.35–0.67) 0.53–0.88
Pearson’s r (n.u) 0.19–0.92 −0.15–0.97 0.015
0.66 0.32
(0.38–0.78) (0.08–0.56)