Table 1.
Tissue weights in postnatal day (P) 14 and P45 male mice.
| Tissue/Measure | Control | Early Overnutrition | p-value |
|---|---|---|---|
| P14 | |||
| nasoanal length (cm) | 6.6 (6.5–6.7) | 7.0 (6.9–7.1) | **<0.001 |
| eWAT (mg/g bw) | 2.345 (2.090–3.033) | 5.388 (3.703–8.159) | **<0.001 |
| rpWAT (g) | 0.014 (0.010–0.017) | 0.033 (0.026–0.044) | **<0.001 |
| rpWAT (mg/g bw) | 1.379 (0.918–1.643) | 2.580 (2.024–3.320) | **<0.001 |
| mWAT (g) | 0.045 (0.042–0.056) | 0.074 (0.065–0.081) | **<0.001 |
| mWAT (mg/g bw) | 4.740 (4.080–5.170) | 5.866 (5.014–6.152) | *0.011 |
| pancreas (g) | 0.022 (0.020–0.025) | 0.029 (0.027–0.033) | *0.001 |
| pancreas (mg/g bw) | 2.110 (2.032–2.428) | 2.220 (2.066–2.413) | 0.707 |
| liver (g) | 0.399 (0.360–0.442) | 0.557 (0.544–0.582) | **<0.001 |
| liver (g/g bw) | 0.038 (0.037–0.042) | 0.043 (0.041–0.044) | *0.016 |
| kidney (g) | 0.068 (0.066–0.072) | 0.088 (0.083–0.091) | **<0.001 |
| kidney (mg/g bw) | 6.541 (6.323–7.455) | 6.584 (6.349–7.125) | 0.689 |
| spleen (g) | 0.056 (0.049–0.063) | 0.078 (0.065–0.104) | **<0.001 |
| spleen (mg/g bw) | 5.365 (4.714–6.108) | 6.043 (5.138–7.998) | 0.110 |
| P45 | |||
| nasoanal length (cm) | 10.3 (10.0–10.8) | 10.5 (10.2–10.6) | 0.796 |
| eWAT (g) | 0.559 (0.386–0.750) | 1.019 (0.816–1.052) | *0.008 |
| eWAT (mg/g bw) | 14.66 (10.47–19.34) | 22.03 (19.06–22.90) | *0.039 |
| rpWAT (g) | 0.184 (0.076–0.211) | 0.206 (0.164–0.281) | 0.199 |
| mWAT (g) | 0.372 (0.256–0.461) | 0.598 (0.355–0.847) | 0.091 |
| pancreas (g) | 0.364 (0.300–0.397) | 0.395 (0.350–0.409) | 0.272 |
| liver (g) | 1.693 (1.634–1.989) | 2.101 (1.898–2.200) | 0.061 |
| kidney (g) | 0.352 (0.308–0.387) | 0.412 (0.394–0.423) | *0.014 |
| kidney (mg/g bw) | 9.395 (8.425–9.897) | 9.258 (8.697–9.551) | 0.908 |
| spleen (g) | 0.164 (0.122–0.181) | 0.161 (0.131–0.172) | 0.981 |
Values represent median (interquartile range), n = 11–13 per group at P14 and n = 5 per group at P45. P14 spleen (g and mg/g bw) and P14 and P45 kidney (mg/g bw) weights analyzed by Mann-Whitney, all others by unpaired t-test. eWAT: epididymal white adipose tissue; rpWAT: retroperitoneal white adipose tissue; mWAT: mesenteric white adipose tissue; bw: body weight. *p < 0.05, **p < 0.001.