Table II.
Genotype and allele frequencies in the primary brain tumor and the healthy control groups and association of SOD2 gene rs4880 polymorphism with the risk of primary brain tumor susceptibility according to different models of inheritance.
| Group, n (%) | |||||
|---|---|---|---|---|---|
| Controls (n=120) | Cancer patients (n=105) | OR (95% CI) | χ2 | P-value | |
| SOD2 rs4880 | |||||
| C allele | 113 (47.1) | 98 (46.7) | 1.00 (reference) | ||
| T allele | 127 (52.9) | 112 (53.3) | 1.02 (0.69-1.50) | 1.01 | 0.929 |
| Codominant | |||||
| CC | 29 (24.2) | 25 (23.8) | 1.00 (reference) | ||
| CT | 55 (45.8) | 48 (45.7) | 1.01 (0.50-2.07) | 0.01 | 0.970 |
| TT | 36 (30.0) | 32 (30.5) | 1.03 (0.47-2.25) | 0.01 | 0.933 |
| Dominant | |||||
| CC | 29 (24.2) | 25 (23.8) | 1.00 (reference) | ||
| CT+TT | 91 (75.8) | 80 (76.2) | 1.02 (0.53-1.97) | 0.01 | 0.978 |
| Recessive | |||||
| CC+CT | 84 (70.0) | 73 (69.5) | 1.00 (reference) | ||
| TT | 36 (30.0) | 32 (30.5) | 0.96 (0.52-1.75) | 0.02 | 0.880 |
| Overdominant | |||||
| CC+TT | 65 (54.2) | 57 (54.3) | 1.00 (reference) | ||
| CT | 55 (45.8) | 48 (45.7) | 1.00 (0.57-1.74) | 0.01 | 0.986 |
SOD2, superoxide dismutase 2; OR, odds ratio; CI, confidence interval.