Table II.
Univariate analysis investigating the correlation between cancer/testis antigen expression and the patients' clinical features.
| NY-ESO-1 | MAGE-A4 | |||||
|---|---|---|---|---|---|---|
| Factors | (+) | (−) | P-value | (+) | (−) | P-value |
| Mean age, years | 36.7 | 61.4 | <0.001 | 35.8 | 60 | <0.001 |
| Sex, n | ||||||
| Male | 7 | 42 | 0.146 | 6 | 43 | 0.987 |
| Female | 9 | 24 | 4 | 29 | ||
| Tumor location, n | ||||||
| Extremity | 10 | 43 | 0.842 | 5 | 48 | 0.302 |
| Trunk | 6 | 23 | 5 | 24 | ||
| Tumor depth, n | ||||||
| Superficial | 1 | 11 | 0.29 | 0 | 12 | 0.162 |
| Deep-seated | 15 | 55 | 10 | 60 | ||
| Tumor stage, n | ||||||
| I or II | 4 | 24 | 0.39 | 3 | 25 | 0.768 |
| III or IV | 12 | 42 | 7 | 47 | ||
| Tumor size, cm | ||||||
| ≤5 | 5 | 27 | 0.477 | 4 | 28 | 0.946 |
| >5 | 11 | 39 | 6 | 44 | ||
| Synovial sarcoma | ||||||
| Yes | 10 | 7 | <0.001 | 9 | 8 | <0.001 |
| No | 6 | 59 | 1 | 64 | ||
| Myxoid liposarcoma | ||||||
| Yes | 5 | 4 | 0.004 | 0 | 9 | 0.236 |
| No | 11 | 62 | 10 | 73 | ||
| Total n | 16 | 66 | 10 | 72 | ||
NY-ESO-1, New York-esophageal squamous cell carcinoma-1; MAGE-A4, melanoma-associated antigen-4.