Table III.
Table of MSI cases with MSI polymerase chain analysis and BRAF mutation analysis.
| Case | MSI | BRAF | Methylation |
|---|---|---|---|
| 1 | MSI-H | − | + |
| 2 | MSI-H | + | + |
| 3 | MSI-H | − | + |
| 4 | MSI-H | + | + |
| 5 | MSI-H | − | − |
| 6 | MSI-H | − | + |
| 7 | MSI-H | − | − |
| 8 | MSI-H | + | + |
| 9 | MSI-L | − | − |
| 10 | MSI-H | − | − |
| 11 | MSI-H | + | Not determined |
| 12 | MSI-H | − | Not determined |
| 13 | MSI-H | − | − |
| 14 | MSI-H | + | + |
| 15 | MSI-H | − | + |
| 16 | MSI-H | + | + |
| 17 | MSI-H | + | + |
| 18 | MSI-H | − | + |
| 19 | MSI-H | + | + |
| 20 | MSI-H | − | − |
| 21 | MSI-H | − | − |
| 22 | MSI-H | − | − |
| 23 | MSI-H | + | + |
| 24 | MSI-H | − | − |
| 25 | MSI-H | − | − |
| 26 | MSI-H | − | − |
| 27 | MSI-H | − | + |
| 28 | MSI-H | − | + |
| 29 | MSI-H | − | + |
| 30 | MSI-H | + | + |
| 31 | MSI-H | + | + |
| 32 | MSI-L | − | + |
| 33 | MSI-L | − | + |
| 34 | MSI-H | + | + |
| 35 | MSI-H | − | + |
| 36 | MSI-H | + | + |
| 37 | MSI-L | − | − |
A total of 37 MSI cases were selected from the present cohort. Twenty-four (64.9%) samples did not have the c.1799T>A mutation in BRAF exon 15. MLH1 methylation was determined in 23 cases. For NGS analysis 12 suspected samples were selected (BRAF and MLH1 negative). +, positive status; -, negative status; MSI, microsatellite instability; -L, low; -H, high