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. 2019 Feb 21;21(2):e12997. doi: 10.2196/12997

Table 1.

Characteristics of the included studies.

Study, design, and country Learning modality Type of participants Number of sites and participants Intervention duration Type of outcome
Digital education versus traditional education

Chaikoolvatana 2007 [25]; RCTa; Thailand Ib: Computer based learning (CBL); Cc: face-to-face lectures Final year pharmacy students I: 43, C: 40 I: 2 hours; C: 2 3-hour sessions; (over 2 months) (1) Knowledge; (2) skills

Desimone 2012 [29]; RCT; United States I: PDAd version education materials; C: Printed materials Internal medicine residents I: 11, C: 11 Over 1 month Knowledge

Diehl 2017 [34]; RCT; Brazil I: Online game; C: Face-to-face lectures and activities Primary Care Physicians I: 94, C: 76 4 hours (over 3 months) Skills

Hibbert 2013 [30]; RCT; Australia I: Training Video; C: No intervention (usual revision) Second year medical students I: 12, C: 10 Over 2 Weeks Skills

Sperl-Hillen 2010 [26]; cRCTe; United States I: Simulation Software; C: No intervention Primary Care Physicians and their patients I: 20 sites, (1847 patients), C: 21 sites, (1570 patients) 5.5 days; (over 6 months) Patient outcomes; Economic impact

Sperl-Hillen 2014 [32]; cRCT; United States I: Simulation software; C: No intervention (Not assigned learning cases) Family/ internal medicine residents I: 10 sites (177 residents), C: 9 sites (164 residents) Over 6 months Knowledge; Skills
Blended learning versus traditional education

Gregory 2011 [28]; cRCT; United Kingdom I: Web-based intervention and practical workshops; C: No intervention Paediatric doctors, nurses, psychologists, dieticians, and their patients I: 13 sites (356 patients), C: 13 sites (333 patients) Over 12 months Skills; Patient outcomes; Economic impact

Ngamruengphong 2011 [33]; RCT; United States I: Standard education+30 min didactic lecture, a pocket card, and monthly e-mail reminders that consisted of the lecture content; C: Standard residency education Primary care residents I: 20, C: 19 Over 2 months Knowledge
Digital education versus digital education

Billue 2012 [21]; RCT United States; Estrada 2011[23]; RCT United States; Crenshaw 2010[22]; RCT; United States I: Web-based intervention with feedback; C: Web-based intervention without feedback Family/ general/ internal medicine physicians I: 48 physicians (479 patients), C: 47 physicians (466 patients) Over 2 years Patient outcomes

Brendenkamp 2013 [31]; RCT; United States I: Simulation (High fidelity Mannequin); C: Web-based intervention Staff nurses I: 47, C: 49 Not reported Knowledge

Schroter 2011 [27]; RCT; United Kingdom I: Web-based learning + Diabetes Needs assessment tool (DNAT); C: Web-based learning without DNAT Diabetes doctors and nurses I: 499, C: 498 Over 4 months Knowledge
Blended learning versus digital education versus traditional education

O'Connor 2009 [24]; RCT; United States Group A: No intervention; Group B: Simulated web-based learning; Group C: simulated case-based physician learning + physician opinion leader feedback Primary care physicians and their patients Group A: 100 physicians, 691 patients; Group B: 100 physicians, 725 patients; Group C: 99 physicians, 604 patients Not reported Patient outcomes

aRCT: randomized controlled trial.

bI: intervention group.

cC: control group.

dPDA: Personal Digital Assistance.

ecRCT: cluster RCT.