Table 1.

Medications Used in Swine for the Duration of the Study, Segregated into Those Relevant to the Ischemic Mitral Regurgitation Induction Procedure and Those Relevant to the Mitral Valve Repair Procedure

Ischemic Mitral Regurgitation Procedure				Mitral Valve Repair Procedure
Drug	Dosage/Frequency	Route	Purpose	Drug	Dosage/Frequency	Route	Purpose
Amiodarone	600 mg SID, 3 d prior	PO	Anti‐arrhythmic	Aspirin	81 mg SID, 3 d prior	PO	Anti‐platelet
Aspirin	81 mg SID, 3 d prior	PO	Anti‐platelet	Plavix	75 mg SID, 3 d prior	PO
Plavix	75 mg SID, 3 d prior	PO		Solumedrol	200 to 500 mg, once	IV	Anti‐inflammatory
Ketamine	22 mg/kg, once	IM	Sedative cocktail	Cefazolin	22 to 25 mg/kg, once before surgery and then PRN	IV	Antibiotic
Acepromazine	1.1 mg/kg, once	IM		Carprofen	3 mg/kg, once before surgery and then PRN	IV	NSAID
Atropine	0.05 mg/kg, once	IM		Ketamine	22 mg/kg, once	IM	Sedative cocktail
Isoflurane	1% to 2% in 100% oxygen	Inhalant	Anesthetic	Acepromazine	1.1 mg/kg, once	IM
Amiodarone	8 mg/kg	IV	Anti‐arrhythmic	Atropine	0.05 mg/kg, once	IM
Cefazolin	22 to 25 mg/kg	IV	Antibiotic	Isoflurane	1% to 2% in 100% oxygen	Inhalant	Anesthetic
Carprofen	3 mg/kg	IV	NSAID	Euthasol	80 mEq	IV	Termination

IV indicates intra venous; IM, intra muscular; PO, per os (i.e. drug given orally); PRN, pro re nata (as needed); SID, Semel in Die (once a day).