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. 2019 Mar 6;17:29. doi: 10.1186/s12958-019-0473-z

Fig. 5.

Fig. 5

Schematized “coagulation cascade” pathway derived from proteins shared across all seasons. Adapted from KEGG Pathway Database of “Coagulation and Complement Cascade” (map04610; http://www.genome.jp/kegg/pathway.html). This diagram shows the roles of the F12 protein (Coagulation factor XII; yellow color), in the intrinsic pathway and the F2 protein (Prothrombin; green color), in the extrinsic pathway of the cascade, leading to the “fibrin degradation products”