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Levels of TfR1 are elevated and DMT1 reduced in PHD2 knockdown (KD) mice. Western blot analysis of TfR1 and DMT1 levels in striatal tissues isolated from PHD2 KDs versus control mice. Data are reported as percentage PHD2 control normalized to actin; *p < 0.01 versus PHD2; Tukey's multiple-comparison test.
