Table 6.
Treatment | q-value | ||||||||
---|---|---|---|---|---|---|---|---|---|
Time | Phylum | Genus | C | L | D | M | L+M | < 0.05 | < 0.10 |
T2 | Bacteroidetes | Parabacteroides | 0.27 ± 0.16 | 0.12 ± 0.10 | 0.25 ± 0.11 | 0.05 ± 0.02 | 0.18 ± 0.14 | M vs. C, D, L+M | |
Chlamydiae | Chlamydia | 0.20 ± 0.24 | 0.00 ± 0.00 | 0.02 ± 0.04 | 0.02 ± 0.02 | 0.13 ± 0.04 | L vs. C, L+M vs. L, D, M |
L vs. M | |
Cyanobacteria | o_YS2;f_;g_ | 0.24 ± 0, 16 | 0.06 ± 0.06 | 0.09 ± 0.07 | 0.04 ± 0.01 | 0.04 ± 0.02 | C vs. L, M, L+M | ||
Firmicutes | Lactobacillus | 5.44 ± 2.51 | 1.98 ± 1.18 | 1.98 ± 0.99 | 9.18 ± 5.24 | 6.87 ± 4.66 | L, D vs. M, L+M | C vs. L, D | |
Firmicutes | Dorea | 1.13 ± 0.25 | 0.61 ± 0.18 | 0.83 ± 0.59 | 1.37 ± 0.48 | 1.45 ± 0.73 | C, M, L+M vs. L | ||
Firmicutes | f_Peptostreptococcaceae;g_ | 0.41 ± 0.09 | 0.78 ± 0.21 | 0.54 ± 0.21 | 0.77 ± 0.29 | 0.42 ± 0.22 | C, L+M vs. L, M | ||
Firmicutes | Faecalibacterium | 4.01 ± 1.95 | 2.36 ± 0.46 | 2.58 ± 2.02 | 3.48 ± 0.95 | 1.66 ± 0.51 | M vs. L+M | L vs. M | |
Firmicutes | Mitsuokella | 0.14 ± 0.12 | 0.37 ± 0.54 | 0.62 ± 0.81 | 0.59 ± 0.17 | 0.02 ± 0.03 | C vs. M L+M vs. L, M |
||
Firmicutes | L7A_E11 | 0.03 ± 0.01 | 0.05 ± 0.02 | 0.05 ± 0.06 | 0.02 ± 0.01 | 0.06 ± 0.03 | L, L+M vs. M | ||
Proteobacteria | o_RF32;f_;g_ | 0.05 ± 0.04 | 0.006 ± 0.007 | 0.00 ± 0.00 | 0.01 ± 0.01 | 0.04 ± 0.05 | C vs. D | C vs. L, M M vs. L+M |
|
Spirochaetes | Treponema | 0.22 ± 0.23 | 0.03 ± 0.03 | 0.14 ± 0.13 | 0.03 ± 0.05 | 0.15 ± 0.11 | C, L+M vs. L, M | ||
T3 | Actinobacteria | f_Coriobacteriaceae;_ | 0.001 ± 0.002 | 0.013 ± 0.031 | 0.06 ± 0.40 | 0.038 ± 0.022 | 0.083 ± 0.045 | C vs. D, M, L+M L vs. D, L+M |
|
Actinobacteria | f_Coriobacteriaceae;g_ | 0.036 ± 0.025 | 0.048 ± 0.080 | 0.17 ± 0.10 | 0.22 ± 0.18 | 0.36 ± 0.29 | C vs. D, M, L+M L vs. L+M |
L vs. D | |
Actinobacteria | Collinsella | 0.013 ± 0.014 | 0.013 ± 0.033 | 0.087 ± 0.068 | 0.053 ± 0.027 | 0.16 ± 0.15 | C, L vs. D, M, L+M M vs. L+M |
||
Bacteroidetes | f_S24-7;g_ | 0.25 ± 0.16 | 0.50 ± 0.31 | 0.90 ± 0.76 | 0.86 ± 0.90 | 1.20 ± 0.52 | C vs. L+M | ||
Firmicutes | Megasphaera | 5.95 ± 1.29 | 4.04 ± 4.28 | 7.21 ± 2.02 | 13.46 ± 2.84 | 12.55 ± 3.75 | C, L, D vs. M, L+M | ||
Firmicutes | Mogibacterium | 0.052 ± 0.040 | 0.069 ± 0.051 | 0.011 ± 0.010 | 0.003 ± 0.008 | 0.012 ± 0.020 | L vs. M | C vs. M L vs. D, L+M |
|
Proteobacteria | Escherichia | 0.028 ± 0.063 | 0.003 ± 0.006 | 0.068 ± 0.080 | 0.89 ± 2.17 | 0.076 ± 0.17 | L vs. D | ||
Tenericutes | o_RF39;f_;g_ | 0.16 ± 0.15 | 0.48 ± 0.47 | 0.24 ± 0.28 | 0.011 ± 0.012 | 0.018 ± 0.021 | L vs. M, L+M |
Values are means ± standard deviations. “o,” “f,” and “g” indicate the order, family, and genus, respectively. Some operational taxonomic units (OTUs) could not be assigned to a genus because the sequence was absent from the database. The significance of differences was evaluated using the Kruskal–Wallis test followed by the post hoc Mann–Whitney U-test with the Benjamin–Hochberg false discovery rate correction (q < 0.10). T2, Final day of Phase 1 (day 40 post-weaning); T3, final day of Phase 2 (day 90 post-weaning).