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Amyloid beta intracellularly accumulates in the hippocampal CA1 region of 5XFAD mice at 10 weeks of age.
(A, B) Brain slices of wild-type and FAD mice were subjected to immunostaining with anti-amyloid beta specific antibody, 6E10 under the optical microscope (original magnification, 20×). Scale bar: 100 μm for A and B, 50 μm for B’. Arrows in B’ indicate neurons with intracellular amyloid beta-positive signals. FAD: Family Alzheimer’s disease.
