Figure 1.

Schematic diagram of dorsal root ganglion (DRG) structure and cell types composition.

(A) A diagram of a DRG. The sensory neurons cell body is located within the DRG, with central and peripheral axon extensions. The motor neurons project out from the ventral horn of the spinal cord and combine with the peripheral sensory neurons to form the sciatic nerve. (B) An illustration of the prominent cells within the DRG. The satellite glial cells (SGCs) surround the neuronal cell bodies, whilst the Schwann cells (SCs) ensheath and myelinate single or multiple axon fibres, and finally the macrophages are present for the immune response.