Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 10;28(6):806–821. doi: 10.1111/bpa.12626

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Authors Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

TREX1 positive cells are microglia and/or macrophages. A. Dual staining of frozen tissue from a case of RVCL with anti‐MHC II (top panel, green) and anti‐CD68 (bottom panel, green), microglial markers, and anti‐TREX1 (red). Nuclei are counterstained with TO‐PRO‐3 (blue). Scale bar represents 28 μm. B. Two examples (upper and lower panels) of dual staining of formalin‐fixed, paraffin‐embedded human brain tissue from a normal control with RCA‐1 (left panel, green), a microglial/macrophage and endothelial cell marker, and anti‐TREX1 (red). Nuclei are counterstained with TO‐PRO‐3 (blue). Some cells stained with RCA‐1 but not TREX1 are endothelial cells based on their morphology. Scale bars represent 28 μm on top panel and 14 μm on bottom panel.