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Thy1-null mice and MSCs do not have altered global methylation levels. A) Epididymal adipose tissue from wild-type C57BL/6 mice and Thy1-knockout (TKO) mice was analyzed for global CpG DNA methylation levels by ELISA. Results from adipose tissue from wild-type mice were normalized to 1. B) Bone marrow–derived MSCs from wild-type C57BL/6 and Thy1-knockout mice were analyzed for global DNA methylation as described; n = 5 animals/strain.
