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. 2018 Nov 28;33(3):4077–4088. doi: 10.1096/fj.201801851R

Figure 4.

Figure 4

Knee loading decreases expression of MMP-13 and prevents abnormal changes in articular cartilage and bone mass. A–C) Western blot analysis of expression of MMP-13 (A, B) and relative intensity of MMP-13/β-actin (C). D–J) Representative H&E-stained images (D–G) and quantification of CC/TAC (H), thickness of SBP (SBP.Th) (I), and B.Ar/T.Ar (J). Double arrows indicate thickness of hyaline cartilage (HC) and calcified cartilage (CC). Scale bars, 500 (D, F) and 50 (E, G) µm (n = 10/group). *P < 0.05, **P < 0.01, ***P < 0.001, P > 0.05. N.s., not significant.