Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A–C) The changes in the secondary structures are responsible for the larger structural fluctuations following deletions of the core domains residues, evidenced by the time evolution of secondary structure profiles. D–F) The superposed core domain structures of the final conformations (blue) of 94-341p53β (D), Δ133p53β (E), and Δ160p53β (F) with respect to their initial structure (red) revealed a larger deviation of DNA-binding motif helix H2.
