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. 2019 Jan 24;9(3):901–909. doi: 10.1534/g3.118.200863

Figure 2.

Figure 2

Feminizing mutations enhance lethality in mir-35-41(nDf50) XX animals. A) Top: schematic of crosses performed to generate progeny scored in graph. All males were XX males generated via null mutations in tra-2 and xol-1. XX males were crossed to XX hermaphrodites or females of the three indicated genotypes. Bottom: percent lethality of progeny of crosses illustrated in schematic. The crosses were conducted on RNAi plates, so RNAi affects the maternal and zygotic contribution of sup-26 in the progeny. Sup-26(RNAi) and tra-2(e2020gf) enhance XX lethality in mir-35-41(nDf50). Alleles used are tra-2(e1095lf), tra-2(e2020gf), xol-1(y9). B-C) Percent lethality in mir-35-41(nDf50) combined with her-1(null) or tra-1 or tra-2 RNAi. Mean and standard error for three to four biological replicates are shown.