Table 2. Genotype frequencies for OLFML3 mutation c.590G>A in severely affected and unaffected dogs.
| Genotype for OLFML3 | AA | AG | GG | TOTAL |
|---|---|---|---|---|
| Clinical status | ||||
| GWAS dogs1 | ||||
| Glaucoma | 7 | 0 | 0 | 7 |
| Severe goniodysgenesis | 9 | 1 | 0 | 10 |
| Unaffected | 1 | 19 | 22 | 42 |
| Replication dogs | ||||
| Glaucoma | 2 | 0 | 0 | 2 |
| Severe goniodysgenesis | 3 | 1 | 0 | 4 |
| Unaffected | 0 | 17 | 8 | 25 |
| TOTALS | ||||
| Glaucoma | 9 | 0 | 0 | 9 |
| Severe goniodysgenesis | 12 | 2 | 0 | 14 |
| Unaffected | 1 | 36 | 30 | 67 |
1
Dogs that were included in the genome wide analysis (GWAS dogs) are shown separately from dogs in the replication set that were only tested for OLFML3.