CUSUM analysis of complete excision rate of bengin breastlesions treated by ultrasound-VAE. Acceptable excision rate more then 80%with unacceptable failure rate of 40%. Type 1 error (α) of 0.05 and type 2 error (β) of 0.2. Radiologist 1 (a, d). Radiologist 2 (b, e). Radiologist 3 (c, f). CUSUM, cumulative summation; US-VAE, ultrasound-guided vacuum-assisted excision.