Table 3.
Differences of dPET and MR DCE parameters between tumor and normal prostate
Parameter | Peripheral zone | Non-peripheral zone | ||||||
N | Mean difference a | 95% CI | p value† | N | Mean difference a | 95% CI | p value† | |
dPET | ||||||||
K1 | 35 | 0.332 | 0.266,0.398 | <0.001 | 4 | 0.071 | −0.078.0.219 | 0.229 |
DCE: Quantitative | ||||||||
ktrans | 37 | 0.418 | 0.220,0.617 | <0.001 | 8 | 0.083 | 0.014,0.151 | 0.025 |
kep | 37 | 0.121 | 0.070,0.172 | <0.001 | 8 | 0.613 | 0.285,0.941 | 0.003 |
ve | 37 | 0.026 | −0.028,0.080 | 0.333 | 8 | −0.169 | −0.408,0.070 | 0.139 |
iAUC | 37 | 2.371 | 0.154,4.589 | 0.037 | 8 | 2.621 | −1.511,6.753 | 0.177 |
DCE: Semi-quantitative | ||||||||
in | 37 | 0.357 | 0.223,0.490 | <0.001 | 8 | 0.314 | 0.080,0.549 | 0.016 |
out | 37 | −0.009 | −0.037,0.018 | 0.496 | 8 | −0.030 | -0.050,–0.010 | 0.010 |
ttp | 37 | −0.154 | -0.271,–0.037 | 0.011 | 8 | −0.181 | −0.398, 0.037 | 0.090 |
at | 37 | 0.007 | −0.014,0.027 | 0.513 | 8 | 0.087 | −0.073, 0.246 | 0.240 |
pei | 37 | 0.171 | 0.114,0.228 | <0.001 | 8 | 0.086 | −0.017, 0.189 | 0.088 |
iAUC | 37 | 0.154 | 0.106,0.202 | <0.001 | 8 | 0.096 | 0.017, 0.176 | 0.024 |
CI, confidence interval; DCE, dynamic contrast enhancement; dPET, dynamic positron emission tomography.
Mean difference between tumor and normal sample. †Paired t-test p value.