Table 5.
Pre‐ and Postmatching Distribution of Covariates in Patients With AMI According to the Development of CRS1
| Covariate | Prematching | Postmatching | ||||
|---|---|---|---|---|---|---|
| No‐CRS1 (n=1917) | CRS1 (n=177) | P Value | No‐CRS1 (n=120) | CRS1 (n=120) | P Value | |
| Age, y (median, IQR) | 64 (56, 76) | 77 (67, 82) | <0.001 | 74 (61, 81) | 76.5 (67, 82) | 0.091 |
| Min/max | 25/99 | 42/98 | ··· | 29/99 | 50/91 | ··· |
| ≤60 (n, %) | 741 (38.7) | 22 (12.4) | <0.001 | 27 (22.5) | 16 (13.3) | 0.122 |
| 61 to 70 (n, %) | 513 (26.8) | 34 (19.2) | 24 (20.0) | 22 (18.3) | ||
| 71 to 80 (n, %) | 405 (21.1) | 59 (33.3) | 32 (26.7) | 47 (39.2) | ||
| ≥81 (n, %) | 258 (13.5) | 62 (35.0) | 37 (30.8) | 35 (29.2) | ||
| Female (n, %) | 541 (28.2) | 71 (40.1) | 0.001 | 36 (30) | 48 (40) | 0.104 |
| Hemoglobin at admission, g/L (median, IQR) | 135 (122, 148) | 124 (104.8136.0) | <0.001 | 129 (117.3142.8) | 126 (110, 137.8) | 0.171 |
| Hematocrit at admission, % (median, IQR) | 40.5 (36.6, 44.3) | 37.4 (32.2, 41.1) | <0.001 | 38.55 (35.4, 43.0) | 38.35 (33.5, 42.0) | 0.195 |
| Albumin at admission, g/dL (median, IQR) | 39.0 (36.0, 41.8) | 36.4 (33.4, 39.7) | <0.001 | 37.9 (33.9, 40.7) | 37.45 (34.5, 39.9) | 0.677 |
| Glucose at admission, mmol/L (median, IQR) | 7.8 (6.4, 10.7) | 8.5 (6.6, 11.8) | 0.043 | 8.8 (6.7, 13.9) | 8.6 (6.5, 12.1) | 0.366 |
| Previous coronary artery disease (n, %) | 737 (38.4) | 91 (51.4) | 0.001 | 55 (45.8) | 60 (50) | 0.518 |
| Previous hypertension (n, %) | 1244 (64.9) | 139 (78.5) | <0.001 | 89 (74.2) | 96 (80) | 0.282 |
| Previous diabetes mellitus (n, %) | 633 (33.0) | 77 (43.5) | 0.005 | 41 (34.2) | 49 (40.8) | 0.286 |
| Previous chronic kidney disease (n, %) | 81 (4.2) | 37 (20.9) | <0.001 | 9 (7.5) | 18 (15) | 0.066 |
| Angiography after admission (n, %) | 1587 (82.8) | 82 (46.3) | <0.001 | 61 (50.8) | 63 (52.5) | 0.796 |
| ACEI and/or ARB after admission (n, %) | 1339 (69.8) | 87 (49.2) | <0.001 | 57 (47.5) | 67 (55.8) | 0.196 |
| Diuretics after admission (n, %) | 239 (12.5) | 70 (39.5) | <0.001 | 55 (45.8) | 42 (35) | 0.087 |
ACEI indicates angiotensin‐converting enzyme inhibitor; AMI, acute myocardial infarction; ARB, angiotensin receptor blocker; CRS1, cardiorenal syndrome type 1; IQR, interquartile range.