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. 2018 Sep 20;7(19):e009162. doi: 10.1161/JAHA.118.009162

Table 6.

Postmatching Receiver Operating Characteristic Curve Analysis of NT‐proBNP, eGFR, and hs‐CRP for the Prediction of CRS1

AUC P Value 95% CI
eGFR at admission, mL/(min·1.73 m2) 0.843 <0.001 0.792 to 0.894
NT‐proBNP at admission, pg/mL 0.719 <0.001 0.654 to 0.784
hs‐CRP at admission, mg/L 0.656 <0.001 0.587 to 0.725
NT‐proBNP+eGFR+hs‐CRP 0.863 <0.001 0.816 to 0.910

The differences in the AUC values between the individual biomarkers and their combinations were statistically significant, with P values of 0.0372 (eGFR vs NT‐proBNP+eGFR+hs‐CRP), <0.0001 (NT‐proBNP vs NT‐proBNP+eGFR+hs‐CRP), and <0.0001 (hs‐CRP vs NT‐proBNP+eGFR+hs‐CRP). AUC indicates area under the receiver operating characteristic curve; CI, confidence interval; CRS1, cardiorenal syndrome type 1; eGFR, estimated glomerular filtration rate; hs‐CRP, high‐sensitivity C‐reactive protein; NT‐proBNP, amino‐terminal pro–brain natriuretic peptide.