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. 2018 Sep 29;7(19):e010427. doi: 10.1161/JAHA.118.010427

Figure 3.

Figure 3

Proteoglycans are differentially regulated in pediatric and adult hearts. A, Representative Western blots for versican, biglycan, decorin, osteoglycin, and lumican. Black arrowheads indicate the core protein, while arrows indicate the glycosylated forms. B, Quantification of the protein levels for (i) versican core protein (black border box and whisker) and glycosylated form (gVersican, grey border box and whisker), (ii) biglycan (black border box and whisker) and glycosylated form (gBiglycan, grey border box and whisker), (iii) decorin, (iv) osteoglycin, and (v) lumican. GAPDH served as the loading control. n=12 to 16 per group. Data represent median±interquartile range. *P<0.05 compared with the corresponding control, † P<0.05 compared with the corresponding pediatric group. AU indicates arbitrary units; DCM, dilated cardiomyopathy; NFC, nonfailing control.