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. 2018 Sep 29;7(19):e010427. doi: 10.1161/JAHA.118.010427

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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A disintegrin and metalloproteinases (ADAMs) in pediatric and adult control and failing hearts. A, Representative Western blots for myocardial ADAMs 12, 15, 17, and 19. B, Averaged quantification of protein levels for each ADAM (i through iv). GAPDH represents the loading control. n=12 to 16 per group. Data represent median±interquartile range. *P<0.05 compared with corresponding control, ^† P<0.05 compared with the corresponding pediatric group. AU indicates arbitrary units; DCM, dilated cardiomyopathy; NFC, nonfailing control.