Figure 3.

Remote ischemic preconditioning reduces the IMR and increases the CFR through an increase in hyperemic coronary flow. There was a significant reduction in IMR_calc (A) and the IMR (B) with RIPC, whereas the CFR (C) increased significantly. There was a significant reduction in T_mnH (D) with RIPC, suggesting an increase in hyperemic coronary flow. IMR_calc, CFR and T_mnH: n=15; IMR: n=12; Individual filled symbols represent measurements before or after RIPC in each patient joined with a line, and open symbols and bars represent mean±SD. Bas indicates baseline; CFR, coronary flow reserve; Hyp, hyperemic; IMR, index of microcirculatory resistance; IMR_calc, calculated index of microcirculatory resistance; RIPC, remote ischemic preconditioning; T_mnH, mean transit time during hyperemia.