Table 1.
Study Data Set Characteristics
| Characteristics | All Patients | Patients Without CKD | Patients With CKD | P Value |
|---|---|---|---|---|
| N | 1494 | 1214 (81.3%) | 280 (18.7%) | |
| Age (y), mean (SD) | 61 (14) | 59 (13) | 72 (9) | <0.001 |
| Female sex, x/n (%) | 499/1494 (33%) | 380/1214 (31%) | 119/280 (42%) | <0.001 |
| NSTE‐AMI, x/n (%) | 251/1494 (17%) | 178/1214 (15%) | 73/280 (26%) | <0.001 |
| Laboratory results | ||||
| eGFR (mL/[min·1.73 m²]), mean (SD) | 78 (21) | 85 (14) | 46 (12) | <0.001 |
| Initial hs‐cTnI (ng/L), median (IQR) | 6.5 (3.3, 25.6) | 5.6 (3, 18.2) | 14.7 (6.5, 76.9) | <0.001 |
| Second hs‐cTnI (ng/L), median (IQR) | 9.2 (5.6, 32) | 8.2 (5.5, 24.7) | 17.3 (8.6, 100.1) | <0.001 |
| Cardiovascular risk factor | ||||
| Hypertension, x/n (%) | 1103/1494 (74%) | 833/1214 (69%) | 270/280 (96%) | <0.001 |
| Diabetes mellitus, x/n (%) | 291/1494 (19%) | 197/1214 (16%) | 94/280 (34%) | <0.001 |
| Active smoker, x/n (%) | 349/1493 (23%) | 323/1214 (27%) | 26/279 (9%) | <0.001 |
| Former smoker, x/n (%) | 471/1432 (33%) | 365/1156 (32%) | 106/276 (38%) | 0.036 |
| Hyperlipidemia, x/n (%) | 1101/1494 (74%) | 870/1214 (72%) | 231/280 (82%) | <0.001 |
| Known CAD, x/n (%) | 573/1493 (38%) | 406/1213 (33%) | 167/280 (60%) | <0.001 |
| History of myocardial infarction, x/n (%) | 361/1491 (24%) | 254/1213 (21%) | 107/278 (38%) | <0.001 |
| Family history of CAD, x/n (%) | 533/1492 (36%) | 455/1213 (38%) | 78/279 (28%) | 0.003 |
| Obesity, x/n (%) | 394/1384 (28%) | 319/1124 (28%) | 75/260 (29%) | 0.9413 |
Baseline characteristics of the study data set. Data are presented as cases/number (percentage), mean (SD), or median (IQR), as indicated. CAD indicates coronary artery disease; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; hs‐cTnI, high‐sensitive cardiac troponin I; IQR, interquartile range; NSTE‐AMI, non–ST‐segment elevation myocardial infarction.