TABLE I.
Experimental conditions in the static controls, proximal tubule device, or proximal tubule device with glomerular filtration.
Experimental conditions | Glomerular filter | Proximal tubule τ (dyn/cm2) | Glomerular filtration ΔP (mm Hg) |
---|---|---|---|
Static Transwell | No | N/A | N/A |
Physiological shear, calcium oxalate exposure | No | 0.8 | N/A |
Altered glomerular filtration rate (high shear) | No | 5 | N/A |
High glucose, drug exposure | Yes | 0.2 | 4605 |