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. Author manuscript; available in PMC: 2019 Mar 7.
Published in final edited form as: Prog Retin Eye Res. 2017 Dec 8;64:1–55. doi: 10.1016/j.preteyeres.2017.11.003

Fig. 25.

Fig. 25.

Fundus autofluorescence (AF) imaging. A. Blue-light scanning laser ophthalmoscope FAF image of a normal right eye. Retinal blood vessels are dark and seen in sharp contrast as they block the AF from the retinal pigment epithelium (RPE). The optic nerve head is similarly dark due to the absence of RPE at this location. In addition, as blue light is absorbed by the macular pigment, the central macula (fovea) is also relatively hypo-autofluorescent. B. FAF image of the eye of a patient with Best’s vitelliform macular dystrophy. The vitelliform lesion is intensely autofluroescent. Blue-light scanning laser ophthalmoscope (C) and green-light flash fundus camera (D) FAF imaging of a patient with geographic atrophy (GA). The high contrast of FAF imaging, with absence of the AF in the region of photoreceptor and RPE loss allows the borders of the atrophy to be precisely defined.