Fig. 46.

Varying sized flow voids in the deep vascular plexus in eyes with diabetic macular edema. (A) The cystoid spaces (in teal) are integrated into the volume rendered vascular structure. The cystoid spaces are located below the superficial vascular plexus. (B) The data set was rotated to show the view of the retina from below. The structure of the cystoid spaces is evident and there is a loss of flow signal from the deep vascular layer larger in extent than the cystoid spaces. (C) The imaging data from the cystoid spaces was not shown. The absence of the deep plexus under some areas of the superficial vascular plexus can be seen. (D) With the dataset rotated so the deep plexus is on top, the group of larger cystoid spaces is seen to correlate to a region in which the deep plexus flow data is not apparent. The smaller region of edema has an even smaller flow void (arrow). Reprinted from Spaide (2016b).