Table 1:

Inclusion and exclusion criteria.

Inclusion criteria	Exclusion criteria
– Radically resected patients with colonic adenocarcinoma or signet ring cell carcinoma with high-risk tumors defined as: perforated/pT4NanyM0 (UICC 8th edition)/pTanyNanyM1 with radically resected PM including ovarian metastases – Performance status 0–1 – Age>18 years – Fertile women must use contraceptives – Written informed consent	– Radiologically or clinically proven relapse – Previous CRS with HIPEC – Other malignant diagnoses within the last 2 years – Contraindications to laparoscopy (e. g. severe adhesions, peritonitis) – A history of allergic reaction to oxaliplatin- or other platinum-containing compounds – Renal impairment, defined as GFR<50 mL/min, (Cockcroft-Gault Equation)
	– Myocardial insufficiency, defined as NYHA class>2
	– Impaired liver function defined as bilirubin ≥ 1.5×UNL (upper normal limit)
	– Inadequate hematological function defined as ANC ≤ 1.5 x 109/L and platelets ≤ 100×109/L
	– Any other condition or therapy that in the investigator’s opinion may pose a risk to the patient or interfere with the study objectives