Table 1. Characteristics of the studies included in the meta-analysis.
| Authors, year | Country | Ethnicity | Female/male ratio | Age, y [mean ± SD or median (min—max)] | HWE p-value | ||
|---|---|---|---|---|---|---|---|
| AMD patients | Healthy subjects | AMD patients | Healthy subjects | ||||
| Cheng et al., 2017 | China | Asian | 42/84 | 50/91 | 62.4±9.6 | 63.8±10.2 | 0.117 |
| Liutkeviciene et al., 2016 | Lithuania | Caucasian | 186/201 | 330/352 | 65 (57–93) | 66 (55–97) | 0.664 |
| Ortak et al., 2013 | Turkey | N/A | 79/65 | 84/88 | 67.1 ± 6.9 | 66.1 ± 6.5 | >0.05 |
| Seitzman et al., 2008 | USA | Caucasian | 434/0 | 456/0 | > 60 | >60 | >0.05 |
| Liutkeviciene et al., 2017 | Lithuania | Caucasian | 164/126 | 316/210 | 67 (59.9–67.8) | 68 (60.8–68.3) | 0.528 |
| Liutkeviciene et al., 2018 | Lithuania | Caucasian | 168/99 | 205/113 | 75.4±7.6 | 74.7±8.4 | 0.382 |
AMD: Age-related macular degeneration; N/A: not available; y: years; SD: standard deviation; HEW: Hardy-Weinberg equilibrium.