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. 2019 Mar 7;14(3):e0213624. doi: 10.1371/journal.pone.0213624

Table 3. Summary of meta-analysis results for the association of rs243865 MMP-2 polymorphism with age-related macular degeneration by age.

OR 95% CI P (random-effects model) I2 P (heterogeneity)
AMD patients < 65 y vs healthy subjects < 65 y (N = 3)
CC vs CT+TT 0.88 0.66–1.17 0.44 15% 0.31
AMD patients > 65 y vs healthy subjects > 65 y (N = 3)
CC vs CT+TT 0.90 0.70–1.15 0.41 0% 0.40
AMD patients > 65 y vs AMD patients < 65 y (N = 3)
CC vs CT+TT 1.19 0.78–1.81 0.43 44% 0.43

OR, odds ratio; CI, confidence interval; AMD, age-related macular degeneration; y, age in years; N, number of studies included in each meta-analysis.