Table 3. Summary of meta-analysis results for the association of rs243865 MMP-2 polymorphism with age-related macular degeneration by age.
OR | 95% CI | P (random-effects model) | I2 | P (heterogeneity) | |
---|---|---|---|---|---|
AMD patients < 65 y vs healthy subjects < 65 y (N = 3) | |||||
CC vs CT+TT | 0.88 | 0.66–1.17 | 0.44 | 15% | 0.31 |
AMD patients > 65 y vs healthy subjects > 65 y (N = 3) | |||||
CC vs CT+TT | 0.90 | 0.70–1.15 | 0.41 | 0% | 0.40 |
AMD patients > 65 y vs AMD patients < 65 y (N = 3) | |||||
CC vs CT+TT | 1.19 | 0.78–1.81 | 0.43 | 44% | 0.43 |
OR, odds ratio; CI, confidence interval; AMD, age-related macular degeneration; y, age in years; N, number of studies included in each meta-analysis.