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. 2019 Mar 7;14(3):e0213257. doi: 10.1371/journal.pone.0213257

Table 6. Diagnostic accuracy of the fractional-order parameters in the detection of respiratory alterations in patients with sickle cell disease.

Values obtained in patients with normal values in the spirometric exam and abnormal spirometry.

FrL α C β G H η
Normal exam
    AUC 0.910 0.786 0.763 0.967 0.743 0.892 0.967
    Se (%) 90.48 66.67 76.19 95.24 76.19 90.48 95.24
    Sp (%) 91.30 82.61 65.22 95.65 69.57 91.30 95.65
    Cut-off >0.137 ≤0.606 >0.033 ≤0.623 >14.098 ≤25.06 >0.599
Abnormal exam
    AUC 0.918 0.731 0.624 0.989 0.859 0.850 0.989
    Se (%) 87.50 58.33 66.67 100.00 70.83 79.17 100.00
    Sp (%) 91.30 86.96 65.22 95.65 95.65 91.30 95.65
    Cut-off >0.137 ≤0.598 >0.033 ≤0.623 >18.341 ≤24.931 >0.599

AUC: area under the receiver-operator curve; Se: sensibility; Sp: specificity.