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. 2019 Mar 7;14(3):e0213459. doi: 10.1371/journal.pone.0213459

Table 4. Reproducible features using the Pyradiomics software and simulated delineations with a Dice coefficient of 0.85 on DATASET 1 according to the gray-level discretization.

Sequence Difference in reproducible features distribution (p-value) Highest number of reproducible features
Among FBS Among FBN Number P-Value
FBS FBN
wDIXON-T2-WI 0.14 < 0.0001* 57 37 < 0.001*
ipDIXON-T2-WI 0.69 0.75 62 46 < 0.01*
pc wDIXON-T1-WI 0.28 < 0.001* 66 57 < 0.05*
pc ipDIXON-T1-WI 0.41 < 0.01* 64 59 0.27
T1-WI 0.14 < 0.05* 54 44 0.09
ADC map 1 0.25 43 26 < 0.05*

FBS = Fixed Bin Size (absolute discretization), FBN = Fixed Bin Number (relative discretization). Sequence abbreviations: Water DIXON-T2-WI (wDIXON-T2-WI); In-Phase DIXON-T2-WI (ipDIXON-T2-WI); Post-Contrast Water DIXON-T1-WI (pc wDIXON-T1-WI); Post-Contrast In-Phase DIXON-T1-WI (pc ipDIXON-T1-WI); Apparent Diffusion Coefficient map (ADC map).

* = statistically significantly different among discretizations.