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. 2019 Feb 25;15(2):e1006108. doi: 10.1371/journal.pcbi.1006108

Fig 7. Impact of SGLT2 and NKCC2 inhibition on segmental delivery of Na+, K+, Cl, and fluid, given per kidney.

Fig 7

Notations are analogous to Fig 2. SGLT2 inhibition lowers proximal convoluted tubular transport, whereas NKCC2 inhibition lowers thick ascending limb NaC; transport; both result in diuresis, natriuresis, and kaliuresis. Insets reproduce distal segment and urine values.